St Leonards failed to progress in the FA Cup after they suffered a 2-1 home defeat against Slough Town.
It looked good for Saints when they went in front after Slough defender Paul Barrowcliff deflected a shot from defender Richard Callaway into his own net in the second minute.
But an injury to top scorer Mark Lovell, who was taken off with suspected knee damage after a collision with Slough goalkeeper Jean Zepherin midway through the first half, proved to be the turning point.
Slough got on top and two goals in three minutes in the second half from former Reading player Michael Gilkes turned the tie on its head.
Saints boss Glyn White said: "I'm bitterly disappointed because we found a way to lose a game again. I could not argue with the work rate we have shown but we gave away two bad goals.
"I only hope Mark's injury is not too bad because if we lost him it would be a major blow."
Crawley and Hastings join the Sussex survivors in today's second qualifying round draw.
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