Sussex star Ollie Robinson will lead the new-ball attack for England.
He will move up the pecking order for the second Test of the series against India, starting today.
Robinson returns to Lord’s, scene of his bitter-sweet Test debut versus New Zealand earlier this season.
He has been thrust on to the frontline by injury problems for the hosts.
England are preparing to line-up in a home Test without James Anderson or Stuart Broad for the first time in more than nine years.
Broad has been ruled out of the rest of the five-match LV= Insurance Series after pulling up injured in a warm-up session.
An MRI scan in London yesterday lunchtime revealed a tear to Broad’s right calf.
Meanwhile 39-year-old Anderson complained of a tight quad on the eve of the match and it is highly unlikely that any risks will be taken with his longer-term fitness.
England were already missing Sussex paceman Jofra Archer, who is a long-term absentee with an elbow injury.
Robinson will now take new-ball duties, with Mark Wood recalled and Craig Overton vying with the late call-up Saqib Mahmood for the remaining spot.
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