Arsenal midfielder Granit Xhaka is expected to miss their trip to the Amex.
He has suffered a ruptured inner ligament in his right knee, according to a report in his native Switzerland.
Xhaka is expected to miss at least six weeks.
He has been in fine form of late as the Gunners recover from a poor start to the season.
They head to the Amex after three wins, the last of them in convincing style against arch enemy Tottenham.
,
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules here