Leandro Trossard had a hit-and-miss evening for Belgium as he started against Wales.
The Albion man wasted a great first-half chance and was again off target in the second period.
But he was heavily involved in the Youri Tielemans goal which gave the Red Devils the lead in their Nations League fixture in Cardiff.
It came six minutes after the break as Trossard broke down the right and fed Michy Batshuayi, who rolled the ball into Tielemans’ path.
The Seagulls star had left the action by the time Brennan Johnson’s first international goal gave Wales a point three minutes from time.
The equaliser was a blow to Belgium, who could have closed the gap on group leaders Holland.
The Dutch, with Kjell Scherpen an unused sub, drew 2-2 with Poland and retain a three-point lead in top spot.
Trossard's first-half chance saw him scuff a left-foot effort wide of a largely unguarded net as Batshuayi's shot was deflected into his path.
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