The Reduced Shakespeare Company will attempt to set a world record today when it performs an abridged version of the playwright's works at 37,000ft.
In celebration of the 450th anniversary of the Bard's birth, the live performance will take place in front of passengers on an easyJet flight from Gatwick Airport to Verona.
The actors are hoping to set a Guinness World Record for the highest theatrical performance with the play which will last one hour, an easyJet spokeswoman said.
The performance is part of a wider easyJet campaign to make April 23 National William Shakespeare Day.
Heritage and culture remain one of the key drivers of tourism to the UK, according to Visit Britain, and the airline has run a month-long campaign to promote the best Shakespearean sites to visitors, as well as staging free performances of Shakespeare's work at check-in desks.
The production will take place on board a special edition easyJet plane, complete with a 10ft image of the Bard on the fuselage.
Three actors from the Reduced Shakespeare Company will perform at the front of the aircraft and have been rehearsing in easyJet's Luton training centre in preparation for the show.
Paul Moore, communications director for easyJet, said: "William Shakespeare is Britain's most famous author so easyJet is proud to back the bid to make April 23 his national day."
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