Craig Noone has been given a first Championship start of the season for Albion today.
The winger, so effective off the bench against Doncaster and Portsmouth, comes in for Matt Sparrow as the only change to the side which won Cardiff in midweek.
Kazenga LuaLua is among the five substitutes.
Summer signing Will Hoskins, a debut scorer at Cardiff after coming off the bench, must wait for a first taste of action at The Amex.
Hoskins, sidelined by an abductor muscle problem suffered in pre-season, revealed this morning he felt some reaction to the injury after his outing in South Wales.
He is not risked today at the start of a busy eight-day period which also sees Sunderland and Peterborough visit The Amex.
Will Buckley (hamstring) is also out today along with longer-term absentees Adam El-Abd and Tommy Elphick.
Blackpool have come south without central defender Craig Cathcart, who has been suffering from a stomach bug.
Alex Baptiste, a friend of Hoskins from their schoolboy days in Nottinghamshire, switches from right-back to central defence with boss Ian Holloway keen to add more pace to his line-up.
Albion: Ankergren; Calderon, Greer, Dunk, Painter; Bridcutt, Vincelot, Dicker; Noone, Mackail-Smith, Barnes. Subs: Brezovan, Navarro, Cook, Sparrow, LuaLua.
Blackpool: Gilks; Basham, Baptiste, Evatt, Crainey; Ferguson, Southern; Taylor-Fletcher; M.Phillips, K.Phillips, Clarke. Subs: Halstead, Eardley, Ormerod, Hill, Sutherland.
Ref: Philip Gibbs (Solihull)
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